NOX1 (C-term) Rabbit Polyclonal Antibody
$570.00
3 Weeks*
Specifications
| Product Data | |
| Application | ELISA, IHC, WB |
|---|---|
| Recommended Dilution | ELISA: 1 µg/ml. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot: 1 µg/ml. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to C-terminal residues of Human NOX1. |
| Specificity | This antibody recognizes Human NADPH Oxidase 1 (NOX1). Other species not tested. |
| Buffer | PBS State: Aff - Purified State: Liquid purified IgG fraction Stabilizer: 50% Glycerol Preservative: 0.01% Sodium Azide |
| Concentration | lot specific |
| Purification | Immunoaffinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 65 kDa (Predicted) |
| Gene Name | NADPH oxidase 1 |
| Database Link | |
| Background | The NOX family NADPH protein oxidases are involved in transfer of electrons accross membranes to generate reactive oxygen species. There are 7 family members - NOX1-5, DUOX1 and DUOX2. Expression of NOX1 is highest in colon tissue; it is also found in vascular tissue and can also been induced by a variety of factors including PDGF. It requires interaction with NOXO1 and NOXA1 for superoxide generation. |
| Synonyms | NADPH oxidase 1, NOH1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
Wang, Dashwood, Nian et al
Int J Cancer (2011) 128 (11), 2581-90 DOI: 10.1002/ijc.25610
Wang, Dashwood, Nian et al
Int J Cancer (2011) 128 (11), 2581-90 DOI: 10.1002/ijc.25610
Cited by 64
AI Summary: In this study, OriGene products—specifically Nox1 and Nox4 shRNA plasmids—were used to knock down gene expression in human colon cancer cells, enabling the researchers to investigate the roles of these genes in colon tumor development and NFκB signaling.
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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