ATM Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human ATM around the phosphorylation site of Serine 1981 (E-G-SP-Q-S). |
| Specificity | ATM Antibody AP08052PU detects endogenous levels of total ATM protein. |
| Buffer | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Immunoaffinity Chromatography using epitope-specific immunogen |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | ATM serine/threonine kinase |
| Database Link | |
| Background | ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases). |
| Synonyms | Serine-protein kinase ATM, Ataxia telangiectasia mutated, A-T mutated, ATDC, TEL1, TELO1 |
| Reference Data | |
| Protein Categories | Cancer: Haematopoietic and Lymphoid, Enzyme: Kinases, Immune system diseases, Intracellular Proteins, Nervous system: Neurodegenerative diseases |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.