Peripherin (PRPH) Rabbit Polyclonal Antibody

SKU
AP06284PU-N
Peripherin (PRPH) rabbit polyclonal antibody, Aff - Purified
  $495.00
7 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution IHC:1/50-200
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 430-480 of Human PRPH.
Specificity This antibody detects endogenous levels of Peripherin protein.
(region surrounding Ser454)
Buffer PBS. pH 7.2
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Stabilizer: 50 % Glycerol
Preservative: 0.02 % Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: One year from despatch.
Shipping Blue Ice
Predicted Protein Size ~55 kDa
Gene Name peripherin
Database Link
Background Peripherin is a type III intermediate filament protein that is expressed in peripheral and some central nervous system (CNS) neurons. Peripherin activation is known to be induced by leukemia inhibitory factor (LIF). LIF activates Peripherin by inducing members of STAT transcription factor family to bind to a specific promoter element in the Peripherin gene. IL-6 is also known to induce Peripherin expression. Although it is not essential for neurite formation, peripherin is necessary for cellular intermediate filament network formation. Peripherin, unlike most intermediate filament proteins, has been reported to be modified by tyrosine phosphorylation.
Synonyms PRPH, NEF4, PRPH1
Reference Data
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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