Th Rabbit Polyclonal Antibody

CAT#: AP05922PU-N

Th rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunohistochemistry on frozen sections: 1:1000.
  Western Blot: 1:1000; detects a band of approximately 60kDa in rat caudate cell lysates.
  Immunofluorescence: 1:1000.
• Reactivities: Mammalian, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Tyrosine hydroxylase purified from pheochromocytoma.
• Specificity: This antibody is specific for Tyrosine hydroxylase (TH).
• Formulation: 10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol
  State: Purified
  State: Liquid purified Ig
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: tyrosine hydroxylase
• Database Link:
  Entrez Gene 25085 Rat
  UniProt ID P04177
• Background: Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain.
  Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson
• Synonyms: Tyrosine 3-hydroxylase, TYH