IL2 Rabbit Polyclonal Antibody

CAT#: AP05798AF-N

IL2 rabbit polyclonal antibody, Azide Free

Specifications

Product Data

• Applications: ELISA, FN, WB
• Recommended Dilution: ELISA: 5µg/ml - 10µg/ml.
  Western Blot.
  Functional Assays.
• Reactivities: Human, Monkey
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant human IL-2
• Specificity: This antibody recognises natural and recombinant human IL-2.
• Formulation: Phosphate buffered saline
  State: Azide Free
  State: Liquid purified IgG
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: interleukin 2
• Database Link:
  Entrez Gene 3558 Human
  UniProt ID P60568
• Background: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
• Synonyms: IL-2, TCGF