Ppard (N-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | ELISA: 1:2000 - 1:8000. Western Blot: 1:500 - 1:2000; detects a band of approximately 55kDa in heart whole cell lysates. |
| Reactivity | Human, Monkey, Mouse, Rabbit, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Syntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta. |
| Specificity | This antibody detects peroxisome proliferator-activated receptor, delta (PPARD). |
| Buffer | Phosphate buffered saline pH7.2 containing 0.01% Sodium Azide (NaN3) State: Purified State: Liquid purified IgG |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | peroxisome proliferator activator receptor delta |
| Database Link | |
| Background | PPARD is a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta. PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis. |
| Synonyms | PPAR-beta, Nuclear hormone receptor 1, NUCI, PPARD, NR1C2, PPARB |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins, Transciption Factors |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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