NANS Mouse Monoclonal Antibody [Clone ID: AT1G6]
Specifications
| Product Data | |
| Clone Name | AT1G6 |
|---|---|
| Application | ELISA, ICC, WB |
| Recommended Dilution | ELISA. Western blot (recommended dilution 1:1000). |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Immunogen | Recombinant human NANS (1-359aa) purified from E. coli |
| Specificity | The antibody recognizes human NANS. Other species not tested. |
| Buffer | Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol |
| Concentration | 1mg/ml (determined by BCA assay) |
| Purification | By protein-G affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | N-acetylneuraminate synthase |
| Database Link | |
| Background | NANS (Sialic acids synthease) is an enzyme that functions in the biosynthetic pathways of sialic acids. Expressed ubiquitously, NANS enzymatically catalyzes the H2O-dependent formation of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), both of which are sialic acids. NANS uses N-acetylmannosamine 6-phosphate as a substrate for Neu5Ac synthesis and mannose 6-phosphate as a substrate for KDN synthesis. |
| Synonyms | Sialic acid synthase, SAS, N acetylneuraminate synthase |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Amino sugar and nucleotide sugar metabolism, Metabolic pathways |
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