NANS Mouse Monoclonal Antibody [Clone ID: AT1G6]
Product Data | |
Clone Name | AT1G6 |
---|---|
Application | ELISA, WB |
Recommended Dilution | ELISA. Western blot (recommended dilution 1:1000). |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant human NANS (1-359aa) purified from E. coli |
Specificity | The antibody recognizes human NANS. Other species not tested. |
Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein-G affinity chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | N-acetylneuraminate synthase |
Database Link | |
Background | NANS (Sialic acids synthease) is an enzyme that functions in the biosynthetic pathways of sialic acids. Expressed ubiquitously, NANS enzymatically catalyzes the H2O-dependent formation of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero - D-galacto-nononic acid (KDN), both of which are sialic acids. NANS uses N-acetylmannosamine 6-phosphate as a substrate for Neu5Ac synthesis and mannose 6-phosphate as a substrate for KDN synthesis. |
Synonyms | SAS |
Reference Data | |
Protein Pathways | Amino sugar and nucleotide sugar metabolism, Metabolic pathways |
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