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MHC Class I Mouse Monoclonal Antibody [Clone ID: F21-2]

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SKU
AM08130PU-N
MHC Class I mouse monoclonal antibody, clone F21-2, Purified
Size:
500 ug
Conjugation:
Unconjugated Biotin FITC PE
  $525.00
3 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name F21-2
Application FC, IHC, IP, WB
Recommended Dilution Flow Cytometry (Ref.1-4).
Immunoprecipitation (Ref.1-3).
Immunohistochemistry on Frozen Sections.
Western Blot.
Immunoaffinity Chromatography.
Reactivity Chicken
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Specificity This antibody recognizes a monomorphic epitope on avian MHC Class I molecules (Mr ~ 68 kDa). It also reacts with Turkey MHC Class I.
Buffer 100 mM Borate Buffered Saline, pH 8.2.
No preservatives or amine-containing buffer salts added.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Background MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. (Ref.1-3)Fibroblasts or neurons however only show a low level of antigen.
Synonyms MHC Class 1, HLA Class 1
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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