MHC Class I Mouse Monoclonal Antibody [Clone ID: F21-2]
$695.00
3 Days*
Specifications
| Product Data | |
| Clone Name | F21-2 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1-4) |
| Reactivity | Chicken |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Specificity | This antibody recognizes a monomorphic epitope on avian MHC Class I molecules (Mr ~ 68 kDa). It also reacts with Turkey MHC Class I. |
| Buffer | PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
| Concentration | lot specific |
| Conjugation | FITC |
| Storage | Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Background | MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. (Ref.1-3) Fibroblasts or neurons however only show a low level of antigen. |
| Synonyms | MHC Class 1, HLA Class 1 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.