CD45 / LCA (CD45RC) Rat Monoclonal Antibody [Clone ID: C455.1F]
$465.00
3 Days*
Specifications
| Product Data | |
| Clone Name | C455.1F |
|---|---|
| Application | FC |
| Recommended Dilution | Flow Cytometry: Identification and enumeration of CD45RC+ cells (< / = 0.2 µg/10e6 cells). |
| Reactivity | Mouse |
| Antibody Host | Rat |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Specificity | This antibody recognises an exon C-dependent epitope of CD45 glycoprotein. |
| Buffer | PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent. Label: PE State: Liquid purified Ig fraction. Label: R-Phycoerythrin |
| Concentration | lot specific |
| Conjugation | PE |
| Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | protein tyrosine phosphatase, receptor type, C |
| Database Link | |
| Background | The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. (Ref.1-4) The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species (See also products AM08044). (Ref.1-4)The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform. |
| Synonyms | PTPRC, Leukocyte common antigen, L-CA, T200 |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Cytokines, Growth Factors, Immune system diseases, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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