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CD45 / LCA (CD45RC) Rat Monoclonal Antibody [Clone ID: C455.1F]

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SKU
AM08070PU-N
CD45 / LCA (CD45RC) rat monoclonal antibody, clone C455.1F, Purified
Size:
500 ug
Conjugation:
Unconjugated Biotin FITC PE
  $550.00
3 Days*
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Specifications
Specifications
Product Data
Clone Name C455.1F
Application FC, IP
Recommended Dilution Flow Cytometry: Identification and enumeration of CD45RC+ cells.
Immunoprecipitation.
Reactivity Mouse
Antibody Host Rat
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody recognises an exon C-dependent epitope of CD45 glycoprotein.
Buffer 100 mM Borate Buffered Saline, pH 8.2.
No preservatives or amine-containing buffer salts added.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name protein tyrosine phosphatase, receptor type, C
Database Link
Background The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. (Ref.1-4) The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species (See also products AM08044). (Ref.1-4)The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform.
Synonyms PTPRC, Leukocyte common antigen, L-CA, T200
Reference Data
Protein Categories ADC Targets, CD Markers, Cytokines, Growth Factors, Immune system diseases, Intracellular Proteins, Membrane Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.