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Mouse IgG2a Isotype Control

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SKU
AM03096AF-N
Mouse IgG2a Isotype Control
Size:
100 ug
Conjugation:
Unconjugated
  $275.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application FC
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Specificity The monoclonal antibody PPV-04 is generated against a plant pathogen and does not cross-react with other species. Hence all the background that could be observed when working with this antibody would be a result of general nonspecific interactions between an mouse IgG2a molecule and the respective sample under the particular conditions. Negative Species: Human, Porcine, Mouse, Rat. Other species not tested (expected negative).
Buffer Azide Free PBS, pH~7.4, 0.2 µm filter sterilized
Concentration 1 mg/ml
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Presentation State Azide Free
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Shelf life: one year from despatch.
Shipping Blue Ice
Background The specificity of staining by monoclonal antibodies to target antigens should be verified by establishing the amount of non-specific antibody binding. Especially at higher concentration (more than 15 μg/ml) the antibody staining usually has consignable background. To this end a non-reactive immunoglobulin of the same isotype is included as a negative control for each specific monoclonal antibody used in a particular immunoassay.
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Documents
Resources

file-alt Citations

A(H1N1) vaccination recruits T lymphocytes to the choroid plexus for the promotion of hippocampal neurogenesis and working memory in pregnant mice
Qi, Yang, Xia et al
Brain Behav Immun (2016) 53, 72-83 DOI: 10.1016/j.bbi.2015.11.006
Cited by 39
AI Summary: In this paper, OriGene products—specifically the anti-TCR antibody (Cat# TA347535) and anti-CD4 antibody (Cat# TA809017)—were used to deplete T lymphocyte populations in mice, enabling the authors to demonstrate that T cell recruitment to the choroid plexus is essential for the enhancement of hippocampal neurogenesis and working memory following A(H1N1) vaccination in pregnant mice.
Subversion of early innate antiviral responses during antibody-dependent enhancement of Dengue virus infection induces severe disease in immunocompetent mice
Costa, Fagundes, Valadão et al
Med Microbiol Immunol (2014) 203 (4), 231-50 DOI: 10.1007/s00430-014-0334-5
Cited by 33
AI Summary: OriGene products contributed to this study by providing the mouse β-actin (Actb) qPCR primer (catalog no. MP205604), which was used as a housekeeping gene control in quantitative PCR assays to measure gene expression during Dengue virus infection.
Expression and function of toll-like receptors in peripheral blood mononuclear cells of patients with polymyalgia rheumatica and giant cell arteritis
Álvarez Rodríguez, López-Hoyos, Mata et al
Ann Rheum Dis (2011) 70 (9), 1677-83 DOI: 10.1136/ard.2010.140194
Cited by 37
AI Summary: In this study, OriGene’s TLR7 antibody (TA336183) was used to assess TLR7 expression in peripheral blood mononuclear cells by flow cytometry, contributing to the identification of increased TLR7 expression in patients with polymyalgia rheumatica and giant cell arteritis.
Showing 1-3 of 3 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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