WNT6 (NM_006522) Human Recombinant Protein

SKU
TP762653
Purified recombinant protein of Human wingless-type MMTV integration site family, member 6 (WNT6), full length, with N-GST and C-His tag, expressed in E.coli, 50ug
  $270.00
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region full length of WNT6
Tag N-GST and C-HIS
Predicted MW 67.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_006513
Locus ID 7475
UniProt ID Q9Y6F9 Q8N2E5
Cytogenetics 2q35
RefSeq Size 1700
RefSeq ORF 1095
Summary The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. provided by RefSeq, Jul 2008
Protein Categories Cytokines, Secreated Proteins
Protein Families Adult stem cells, Cancer stem cells, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway, Transmembrane
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway
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Other "WNT6" proteins (3)
SKU Description Size Price
LC401954 Lyophilized WNT6 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401954 Transient overexpression lysate of wingless-type MMTV integration site family, member 6 (WNT6) (as WB positive control) 100 ug
$436.00
TP761929 Purified recombinant protein of Human wingless-type MMTV integration site family, member 6 (WNT6),Pro32-Phe82, with N-terminal His-ABP tag, expressed in E. coli, 50ug 50 ug
$270.00

file-alt Citations

Spatiotemporal interplay between epithelial and mesenchymal cells drives human dentinogenesis
Wei, Wu, Sun et al
Nat Commun (2026)
Cited by 4
AI Summary: OriGene’s WNT6 protein (TP762653) was used to supplement cell cultures, enabling the study of how specific WNT signals from the dental epithelium influence the differentiation of dental papilla cells during human tooth development.
Snippet: DLX6 -AS1 + cells were cultured in the α -MEM medium (Gibco, 12561072) supplemented with either WNT proteins (WNT6, OriGene, TP762653;WNT7B, CUSABIO, CSB -EP026142HU;WNT10B, CUSABIO, CSB - EP026130HU;all at 10 ng/ml) or JAG1 (10 ng/ml, MCE, HY -P70399). S
Showing 1-1 of 1 papers.
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