METRN (NM_024042) Human Recombinant Protein

SKU
TP761464
Purified recombinant protein of Human meteorin, glial cell differentiation regulator (METRN), full length, with N-terminal HIS tag, expressed in E.coli, 50ug
  $270.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length METRN
Tag N-His
Predicted MW 31 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_076947
Locus ID 79006
UniProt ID Q9UJH8
Cytogenetics 16p13.3
RefSeq Size 1109
RefSeq ORF 879
Synonyms C16orf23; c380A1.2
Summary Meteorin regulates glial cell differentiation and promotes the formation of axonal networks during neurogenesis (Nishino et al., 2004 PubMed 15085178).supplied by OMIM, Mar 2008
Protein Categories Intracellular Proteins, Secreated Proteins
Protein Families Secreted Protein
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Other "METRN" proteins (2)
SKU Description Size Price
LC411418 Lyophilized METRN HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY411418 Transient overexpression lysate of meteorin, glial cell differentiation regulator (METRN) (as WB positive control) 100 ug
$436.00

file-alt Citations

A non-apoptotic caspase-8-meteorin pathway in hepatocytes promotes MASH fibrosis
Wang, Moore, Shi et al
Nat Metab (2025)
Cited by 8
AI Summary: OriGene products contributed to this study by providing the mouse Metrn plasmid (no. 215466) for genetic manipulation and the human METRN recombinant protein (TP761464) for functional assays, enabling investigation of meteorin's role in MASH fibrosis.
Snippet: AAV8 containing hepatocyte-specific TBG-Cre recombinase (AAV-TBG-Cre, 107787-AAV8) and the control vector AAV8-TBG-LacZ (105534-AAV8) from Addgene;mouse Metrn plasmid (no. 215466) from Origene;caspase inhibitor Z-VAD-FMK (G7231) from Promega;caspase-8 inhibitor Z-IETD-FMK (FMK007) from R&D Systems;human METRN recombinant protein (TP761464) from Origene
Meteorin-like/Meteorin-β protects heart against cardiac dysfunction
Rupérez, Ferrer-Curriu, Cervera-Barea et al
J Exp Med (2021) 218 (5) DOI: 10.1084/jem.20201206
Cited by 79
AI Summary: OriGene’s recombinant Metrnβ protein was used to treat cells in vitro, enabling the authors to investigate the direct effects of Metrnβ on cardiomyocytes and its role in preventing cardiac hypertrophy.
Snippet: Skip to Main Content Advertisement;cells were treated with the PPARα antagonist GW6471 (1 μmol/liter;Sigma) or Metrnβ (OriGene Technologies, Inc.)
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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