CD163 Mouse Monoclonal Antibody [Clone ID: OTI3B4]

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SKU
TA506386
CD163 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4)
  $447.00
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Specifications
Specifications
Product Data
Clone Name OTI3B4
Application IF, IHC, LMNX
Recommended Dilution IHC 1:150
IF 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD163(NP_004235) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 125.3 kDa
Gene Name CD163 molecule
Database Link
Background The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Aug 2011
Synonyms M130; MM130; SCARI1
Reference Data
Protein Categories ADC Targets, CD Markers, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
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Other "OTI3B4" antibodies (4)
SKU Description Size Price
CF506386 Carrier-free (BSA/glycerol-free) CD163 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4) 100 ug
$620.00
TA506386AM CD163 mouse monoclonal antibody,clone 3B4, Biotinylated 100 ul
$509.00
TA506386BM CD163 mouse monoclonal antibody,clone 3B4, HRP conjugated 100 ul
$509.00
TA506386S CD163 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4) 30 ul
$200.00

file-alt Citations

Spatial Transcriptomics Reveals Transcriptomic and Immune Microenvironment Reprogramming during Thyroid Carcinoma Dedifferentiation
Ning, Zou, Yu et al
Adv Sci (Weinh) (2025)
Cited by 10
AI Summary: OriGene contributed to this study by providing the CD163 antibody (Cat# TA506386), which was used for immunohistochemistry to identify and analyze tumor-associated macrophages in thyroid carcinoma tissue samples.
Snippet: The antibodies used for IHC included: PDCD4 (Proteintech Cat#12587-1-AP), CD163 (OriGene Cat#TA506386), CD20 (Cell Signaling Technology Cat# 48750), CD4 (Proteintech Cat#67786-1-Ig), and CD8 (ZSGB-Bio, Cat#ZA-0508)
IHC
Combinational Deletions of MGF360-9L and MGF505-7R Attenuated Highly Virulent African Swine Fever Virus and Conferred Protection against Homologous Challenge
Ding, Dang, Liu et al
J Virol (2022) 96 (14), e0032922 DOI: 10.1128/jvi.00329-22
Cited by 62
AI Summary: OriGene contributed to this study by providing the anti-CD4 mouse monoclonal antibody (clone UMAB64, catalog no. UM800010CF), which was used for immunostaining to analyze cellular immune responses in vaccinated pigs.
Snippet: CD3 epsilon antibody (DF6594;Affinity Biosciences), anti-CD4 monoclonal antibody (catalog no. 67786-Ig;Proteintech Group), anti-CD4 mouse monoclonal antibody (clone UMAB64) (catalog no. UM800010CF;Origene), anti-CD8a antibody (RPA-T8) (catalog no. 65144-Ig;Proteintech Group), anti-CD163 antibody (EDHu-1) (NB110-40686;Novus), anti-CD68 antibody (Affinity Biosciences;DF7518), IHCeasyCD68 ready
FigureFigureFigure
IHC
Showing 1-2 of 2 papers.
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