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H6PD Mouse Monoclonal Antibody [Clone ID: OTI2A7]

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SKU
TA501257
Anti-H6PD mouse monoclonal antibody, clone OTI2A7 (formerly 2A7)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "H6PD or NM_004285" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2A7
Application FC, IF, IHC, WB
Recommended Dilution WB 1:250~500, IHC 1:50, IF 1:100, FLOW 1:100
Reactivity Human, Monkey
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human H6PD (NP_004276) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 88.7 kDa
Gene Name hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
Database Link
Background There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells.
Synonyms CORTRD1; G6PDH; GDH
Reference Data
Protein Categories Endocrine and metabolic diseases, Intracellular Proteins
Protein Pathways Metabolic pathways, Pentose phosphate pathway
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Other "OTI2A7" antibodies (4)
SKU Description Size Price
CF501257 Carrier-free (BSA/glycerol-free) H6PD mouse monoclonal antibody, clone OTI2A7 (formerly 2A7) 100 ug
$620.00
TA501257AM Anti-H6PD mouse monoclonal antibody, clone OTI2A7 (formerly 2A7), Biotinylated 100 ul
$509.00
TA501257BM Anti-H6PD mouse monoclonal antibody, clone OTI2A7 (formerly 2A7), HRP conjugated 100 ul
$509.00
TA501257S Anti-H6PD mouse monoclonal antibody, clone OTI2A7 (formerly 2A7) 30 ul
$200.00

file-alt Citations

A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia
Jacobs, Lyubenova, Potelle et al
Nature (2025)
Cited by 4
AI Summary: OriGene contributed to this study by providing the mouse anti-H6PD antibody (TA501257), which was used in Western blot experiments to detect H6PD protein levels.
Snippet: Western blots for H6PD and β-actin were performed as described above, but using PVDF membrane (Immobilon P, Milipore), horseradish peroxidase-coupled secondary antibodies, chemiluminescence peroxidase substrate (Immobilon Western Blot reagent, Milipore) and a Cytiva IQ600 system. Mouse anti-H6PD (TA501257, Origene, 1:1,000) and anti-β-actin (A5441, Sigma, 1:5,000) were used as primary antibodies
WB IF
Hexose-6-phosphate dehydrogenase blockade reverses prostate cancer drug resistance in xenograft models by glucocorticoid inactivation
Li, Berk, Alyamani et al
Sci Transl Med (2021) 13 (595) DOI: 10.1126/scitranslmed.abe8226
Cited by 29
AI Summary: OriGene’s anti-H6PD antibody was used in this study to detect H6PD protein levels, enabling the authors to demonstrate H6PD upregulation in prostate cancer tissues and cell models, which was key to linking H6PD activity with drug resistance mechanisms.
Snippet: After incubating with the anti-11β-HSD2 antibody (Santa Cruz Biotechnology;1:3000) and anti-H6PD antibody (OriGene;1:6000) overnight at 4°C, the appropriate secondary antibody was incubated for 1 hour at room temperature;After incubating with the anti–11β-HSD2 antibody (Santa Cruz Biotechnology;1:6000) overnight at 4°C,
Showing 1-2 of 2 papers.
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