WDR6 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, ICC/IF, WB |
|---|---|
| Recommended Dilution | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse |
| Modification | Unmodified |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Buffer | Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 122kDa |
| Gene Name | WD repeat domain 6 |
| Database Link | |
| Background | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Synonyms | FLJ10218; FLJ52552; FLJ56107; MGC126756; MGC142027 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Liu, Shen, Li et al
Adv Sci (Weinh) (2026)
Liu, Shen, Li et al
Adv Sci (Weinh) (2026)
AI Summary: In this study, the anti-WDR6 antibody from OriGene (TA383311) was used to investigate the role of WDR6 protein in the regulation of ferroptosis and drug resistance in chondrosarcoma.
Snippet: … Ferroptosis, an iron‐;The primary antibodies used were mouse anti–β-actin (MBL, M177-3), rabbit anti-REGγ (Abcam, ab157157), anti-FLAG tag (Solarbio, K200001M), anti-HA tag (Abcam, ab9110), anti-WDR6 (ORIGENE, TA383311), anti-STK11 (Proteintech, 10746-1-AP), AMPK (Proteintech, 10929-2-AP), p-AMPK (CST, #2535T), GPX4 (Proteintech, 30388-1-AP), and
Showing 1-1 of 1 papers.
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