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pCMV6-XL5 Mammalian Expression Vector

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SKU
PCMV6XL5
Cloning vector pCMV6-XL5, 10 ug circular vector
  $470.00
In Stock*
Specifications
Specifications
Product Data
C-Tag Tag Free
E. coli Selection Ampicillin (100 ug/mL)
Download Vector Sequence
Components 1 vial of 10 ug lyophilized pCMV6-XL5 vector
Quality Control This vector was sequence verified and restriction-digest confirmed.
Storage Store the vector DNA at -20°C.
Stability Vector DNA is stable for at least one year from date of receipt when stored at -20°C.
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Documents
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file-alt Citations

MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA
Weber, Manzini, Dietrich et al
Cell Death and Differentiation (2026)
Cited by 1
AI Summary: OriGene products pCMV-POLR3A-Flag (Cat# RC207553) and pCMV6-XL5 empty vector (Cat# PCMV6XL5) were used in this study to express and analyze the role of the RNA polymerase III catalytic subunit and as a control, respectively, facilitating investigation of MDM2’s suppression of Pol III-dependent transcription and innate immune signaling.
Snippet: pCMV-P53 wt A. J. Levine [77] pCMV-POLR3A-Flag OriGene Cat# RC207553 pCMV6-XL5 empty OriGene Cat#PCMV6XL5
Leucine rich repeat containing protein 8B (LRRC8B) - A novel modulator of endoplasmic reticulum (ER) stress response
Raja Mathanki, Isaac Newton, Bera
Biochim Biophys Acta Mol Cell Res (2026) 1873 (7), 120195 DOI: 10.1016/j.bbamcr.2026.120195
AI Summary: OriGene’s pCMV6-XL5 plasmid was used as an untagged control in experiments assessing the role of LRRC8B in modulating the endoplasmic reticulum (ER) stress response.
Snippet: The untagged LRRC8B construct was generated by cloning the LRRC8B cDNA sequence between the restriction sites KpnI and NotI in the pEGFP-N1 plasmid and pCMV6-XL5 (# PCMV6XL5;OriGene Technologies, Inc., Rockville, MD, USA) was used as the untagged control. Scramble
Pancreatic Adenocarcinoma Up-Regulated Factor Promotes Epithelial-Mesenchymal Transition and Lung Metastasis in Hepatocellular Carcinoma
Park, Ham, Lee et al
Int J Mol Sci (2026) 27 (14) DOI: 10.3390/ijms27146213
AI Summary: OriGene products, including TGF-βRI and TGF-βRII siRNA oligo duplexes, as well as the pCMV6-XL5, pCMV-TGF-βRI, pCMV-TGF-βRII, pLenti-control, pLenti-PAUF, and pLenti-Luc vectors, were used in this study to manipulate gene expression and investigate the role of PAUF in epithelial-mesenchymal transition and lung metastasis in hepatocellular carcinoma cells.
Snippet: … TGF-βRI (cat# SR322023) and TGF-βRII (cat# SR322024) siRNA oligo duplexes were obtained from OriGene Technologies, Inc. … pCMV6-XL5 (cat# PCMV6XL5), pCMV-TGF-βRI (cat# SC108520), pCMV-TGF-βRII (cat# SC302306), pLenti-control (cat# PS100092), and pLenti-PAUF (cat# RC202244L3), and pLenti-Luc (cat# PS100138) vectors were obtained from OriGene Technologies, Inc
FigureFigureFigure
FTO-Mediated m6A Demethylation of MZF1 Regulates DECR1 to Promote Fatty Acid Oxidation and Exacerbate Myocardial Ischemia/Reperfusion Injury : FTO-Mediated m6A Demethylation of MZF1 Enhances Fatty Acid Oxidation and Aggravates Myocardial I/R Injury
Tian, He, Li et al
Biochem Genet (2025)
Cited by 2
AI Summary: OriGene products, specifically the MZF1 overexpression plasmid and the empty vector plasmid (Cat. No. PCMV6XL5), were used for overexpression experiments to investigate the molecular mechanisms underlying FTO-mediated m6A demethylation of MZF1 in myocardial ischemia/reperfusion injury.
Snippet: For overexpression experiments, 100 ng of plasmids encoding MZF1 (OriGene, Rockville, MD, USA) or empty vector plasmids (OriGene, Cat. No. PCMV6XL5) were mixed
Phosphoglycerate kinase 1 contributes to diabetic kidney disease through enzyme-dependent and independent manners
Sun, Lu, Liu et al
Cell Rep Med (2025)
Cited by 5
AI Summary: In this study, OriGene products—including the GPX1 overexpression vector (Cat# SC119804), empty vector (Cat# PCMV6XL5), control siRNA (Cat# SR30004), UNC5CL siRNA (Cat# SR316676), and Aldh1l1 siRNA (Cat# SR307386)—were used to manipulate gene expression and investigate the molecular mechanisms by which PGK1 contributes to diabetic kidney disease.
Snippet: Primers for qPCR This paper N/A GPX1 overexpression vector Origene Cat# SC119804 Empty vector Origene Cat# PCMV6XL5 Control siRNA Origene Cat# SR30004 UNC5CL siRNA Origene Cat# SR316676 Aldh1l1 siRNA Origene Cat# SR307386
DUSP1 protein's impact on breast cancer: Anticancer response and sensitivity to cisplatin
Metin, Altan, Tercan et al
Biochim Biophys Acta Gene Regul Mech (2025)
Cited by 2
AI Summary: OriGene’s human DUSP1 cDNA (NM_004417) was used in this study to modulate DUSP1 expression in breast cancer cells, enabling the investigation of DUSP1’s role in cell proliferation, migration, and cisplatin sensitivity.
Snippet: sfection 8.0 Reagent, 100 μl of Opti-MEM I, and 2 μg of control nontarget DNA (Cloning vector PCMV6XL5) and human DUSP1 cDNA (OriGene, NM_004417). Cells were seeded into 6-well cell culture plates and allowed to reach a confluence–60-70 %. The growth medi
Showing 1-6 of 481 papers.
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