Stat5b Mouse siRNA Oligo Duplex (Locus ID 20851)
$518.00
In Stock*
Specifications
| Product Data | |
| Purity | HPLC purified |
|---|---|
| Quality Control | Tested by ESI-MS |
| Sequences | Available with shipment |
| Components |
Stat5b (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 20851)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
|
| Stability | One year from date of shipment when stored at -20°C. |
| Shipping | Ambient |
| # of Transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
| Note | Single siRNA duplex (10nmol) can be ordered. |
| Reference Data | |
| RefSeq | NM_001113563, NM_011489, NM_001362682 |
| UniProt ID | P42232 |
| Summary | Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.UniProtKB/Swiss-Prot Function |
| Performance Guaranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Citations
Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells
Marchiori, Scarpa, Kotsafti et al
J. Exp. Clin. Cancer Res. (2019) 38 (1), 190 DOI: 10.1186/s13046-019-1205-0
Marchiori, Scarpa, Kotsafti et al
J. Exp. Clin. Cancer Res. (2019) 38 (1), 190 DOI: 10.1186/s13046-019-1205-0
AI Summary: OriGene products, specifically mouse-specific Atm, Atr, Stat3, Stat5a, Stat5b siRNAs, and Universal Scrambled Negative Control siRNA Duplex, were used in this study to selectively silence target genes and investigate the molecular pathways regulating CD80 expression in colon cancer cells.
Snippet: CT26 cell line was transfected with mouse-specific Atm, Atr, Stat3, Stat5a or Stat5b siRNA (OriGene Technologies, Rockville, USA) and non-silencing siRNA (Universal Scrambled Negative Control siRNA Duplex) (OriGene Technologies)
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
