Foxm1 Mouse siRNA Oligo Duplex (Locus ID 14235)

SKU
SR419879
Foxm1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  $518.00
In Stock*
Specifications
Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
Foxm1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 14235)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_008021
Synonyms AA408308; AW554517; BB238854; Fkh16; Foxm1b; HFH-11B; MPHOSPH2; Mpm2; WIN
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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Documents
Resources

file-alt Citations

FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness
Yuan, Liu, Yu et al
Cell Death Dis (2018) 9 (5), 562 DOI: 10.1038/s41419-018-0631-9
AI Summary: OriGene products contributed to this study by providing FOXM1 and UHRF1 cDNAs in pCMV-XL5 vectors, which were used to investigate the roles of these genes in taxane resistance and cancer stem cell regulation.
Snippet: ersity. These cells were cultured in RPMI-1640 media supplemented with 10% FBS and 1% streptomycin/penicillin. Plasmids, siRNA, and shRNA FOXM1 and UHRF1 cDNAs in pCMV-XL5 vector were purchased from Origene (Rockville, MD, USA). A 2000 bp uhrf1 gene promoter was obtained by the PCR method using genomic DNA as the template, and then subcloned to PCR2.1 vector (Thermo Fisher Scientific, Shanghai,
FigureFigureFigure
Showing 1-1 of 1 papers.
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