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Spic Mouse siRNA Oligo Duplex (Locus ID 20728)

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SKU
SR406758
Spic (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  $518.00
In Stock*

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Other products for "Spic or NM_011461"

Specifications
Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
Spic (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 20728)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_011461
UniProt ID Q6P3D7
Synonyms AU019198; C76795; Prf; Spi-C
Summary Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAAT-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.UniProtKB/Swiss-Prot Function
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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Documents
Resources

file-alt Citations

Spi-C positively regulates RANKL-mediated osteoclast differentiation and function
Go, Oh, Park et al
Exp. Mol. Med. (2020) 52 (4), 691-701 DOI: 10.1038/s12276-020-0427-8
Cited by 10
AI Summary: OriGene products, including the pGFP-C-shLenti-Spi-C vector, pLenti-C-Myc-DDK-Spi-C vector, and Spi-C-targeting siRNA (plus scrambled control siRNA), were used in this study to manipulate Spi-C expression and investigate its role in RANKL-mediated osteoclast differentiation and function.
Snippet: Louis, MO, USA). The pGFP-C-shLenti-Spi-C and pLenti-C-Myc-DDK-Spi-C vectors were purchased from OriGene Technologies Inc The siRNA targeting mouse Spi-C and a scrambled nontargeting siRNA (negative control) were purchased from OriGene Technologies;- Louis, MO, USA). The pGFP-C-shLenti-Spi-C and pLenti-C-Myc-DDK-Spi-C vectors were purchased from OriGene Technologies Inc The siRNA targeting ...
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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