Cd200 Mouse siRNA Oligo Duplex (Locus ID 17470)
$518.00
In Stock*
Specifications
| Product Data | |
| Purity | HPLC purified |
|---|---|
| Quality Control | Tested by ESI-MS |
| Sequences | Available with shipment |
| Components |
Cd200 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 17470)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
|
| Stability | One year from date of shipment when stored at -20°C. |
| Shipping | Ambient |
| # of Transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
| Note | Single siRNA duplex (10nmol) can be ordered. |
| Reference Data | |
| RefSeq | NM_010818, NM_001358443 |
| Synonyms | Mox2; OX2 |
| Performance Guaranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Citations
Local adenoviral delivery of soluble CD200R-Ig enhances antitumor immunity by inhibiting CD200-β-catenin-driven M2 macrophage
Shin, Goh, Ju et al
Mol Ther Oncolytics (2021) 23, 138-150 DOI: 10.1016/j.omto.2021.09.001
Shin, Goh, Ju et al
Mol Ther Oncolytics (2021) 23, 138-150 DOI: 10.1016/j.omto.2021.09.001
Cited by 12
AI Summary: In this study, OriGene’s TrueORF cDNA clones (Cat# MR207779 and Cat# MR207780) were used to generate CD200-overexpressing mouse HNSCC cells (MEER/CD200High), enabling the investigation of CD200's role in tumor growth and immune modulation.
CD200 Induces Epithelial-to-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma via β-Catenin-Mediated Nuclear Translocation
Shin, Goh, Kang et al
Cancers (Basel) (2019) 11 (10) DOI: 10.3390/cancers11101583
Shin, Goh, Kang et al
Cancers (Basel) (2019) 11 (10) DOI: 10.3390/cancers11101583
AI Summary: OriGene's extracellular domain of mouse CD200R1 was used as a PCR template to generate the sCD200R1-Ig construct, enabling the study of CD200/CD200R1 interactions and their role in epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma.
Snippet: AdenoZAPTM 1.2 kits truncating E1 and E3 (OD260, Boise, ID, USA) were used to generate Ad5sCD200R1, which harbored the extracellular domain of mouse CD200 receptor 1 fused with mouse Fc1 of IgG2A (mIgG2A), called sCD200R1-Ig, under the control of the EF1α promoter. To generate sCD200R1-Ig, the extracellular domain of mouse CD200R1 (OriGene, Rockville, MD, USA) was amplified using a polymerase chain reaction (PCR) with primers (Supplementary Figure S6). …
Showing 1-2 of 2 papers.
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in shipping.
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