Cycs Mouse siRNA Oligo Duplex (Locus ID 13063)
$518.00
In Stock*
Specifications
| Product Data | |
| Purity | HPLC purified |
|---|---|
| Quality Control | Tested by ESI-MS |
| Sequences | Available with shipment |
| Components |
Cycs (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 13063)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
|
| Stability | One year from date of shipment when stored at -20°C. |
| Shipping | Ambient |
| # of Transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
| Note | Single siRNA duplex (10nmol) can be ordered. |
| Reference Data | |
| RefSeq | NM_007808 |
| UniProt ID | P62897 |
| Summary | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.UniProtKB/Swiss-Prot Function |
| Performance Guaranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Reviews
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Resources
Citations
Apoptosome-dependent myotube formation involves activation of caspase-3 in differentiating myoblasts
H Dehkordi, Tashakor, O'Connell et al
Cell Death Dis (2020) 11 (5), 308 DOI: 10.1038/s41419-020-2502-4
H Dehkordi, Tashakor, O'Connell et al
Cell Death Dis (2020) 11 (5), 308 DOI: 10.1038/s41419-020-2502-4
Cited by 48
AI Summary: OriGene’s Cycs Mouse siRNA Oligo Duplex (SR401266) was used in this study to specifically silence cytochrome c expression, helping to demonstrate the requirement of cytochrome c in myoblast differentiation and apoptosome-dependent caspase activation.
Snippet: …Cycs Mouse siRNA Oligo Duplex (SR401266) was from OriGene (Rockville, MD);Green-to-red FPX Caspase-3 reporter plasmids, GANES-DEVD-BNLS (50842), RANLS (50843) and single polypeptide FPX biosensor for caspase-3 (60883), and M50054 (ab145906) were purchased from Abcam (Cambridge, UK). …Cycs Mouse siRNA Oligo Duplex (SR401266) was from OriGene (Rockville, MD). …
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
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