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NONO Human siRNA Oligo Duplex (Locus ID 4841)

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SKU
SR321120
NONO (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • SR321120 is the updated version of SR303200.
  $518.00
In Stock*

Frequently Bought Together (4)

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Other products for "NONO or NM_001145408"

Specifications
Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
NONO (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 4841)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_001145408, NM_001145409, NM_001145410, NM_007363
UniProt ID Q15233
Synonyms MRXS34; NMT55; NRB54; P54; P54NRB; PPP1R114
Summary This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. provided by RefSeq, Feb 2009
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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Documents
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file-alt Citations

NonO Is a Novel Co-factor of PRDM1 and Regulates Inflammatory Response in Monocyte Derived-Dendritic Cells
Lee, Jang, Tian et al
Front Immunol (2020) 11, 1436 DOI: 10.3389/fimmu.2020.01436
Cited by 9
AI Summary: In this study, OriGene products—specifically, the PRDM1 (RC217663) and NonO (RC208202) expression plasmids—were used to investigate the interaction and regulatory roles of these proteins in monocyte-derived dendritic cells.
FigureFigureFigure
NonO Is a Novel Co-factor of PRDM1 and Regulates Inflammatory Response in Monocyte Derived-Dendritic Cells
Lee, Jang, Tian et al
Front. Immunol. (2020) 11 DOI: 10.3389/fimmu.2020.01436
Cited by 9
AI Summary: OriGene supplied the human PRDM1 Tagged ORF Clone (RC217363L1V) and siRNA oligo duplexes targeting PRDM1 (SR300437) and NonO (SR321120), which were used for gene expression and knockdown experiments in this study.
Snippet: Plasmids and Transient Transfections Human PRDM1 Tagged ORF Clone PRDM1 (RC217363L1V) and human small interfering Ribonuclic acid (siRNA) oligo duplex exogenous (SR300437;PRDM1 and SR321120;NonO) were purchased from Origene
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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