CMPK2 Human siRNA Oligo Duplex (Locus ID 129607)

SKU
SR315070
CMPK2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  $518.00
In Stock*
Specifications
Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
CMPK2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 129607)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_001256477, NM_001256478, NM_207315, NR_046236
UniProt ID Q5EBM0
Synonyms NDK; TMPK2; TYKi; UMP-CMPK2
Summary This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Feb 2012
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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Documents
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file-alt Citations

CMPK2 promotes microglial activation through the cGAS-STING pathway in the neuroinflammatory mechanism
Gao, Zheng, Liu et al
Sci Rep (2025) 15 (1), 11807 DOI: 10.1038/s41598-025-97232-8
Cited by 13
AI Summary: OriGene products—including the CMPK2 (NM_207315) Human Tagged ORF clone (RC218794), CMPK2 Human siRNA Oligo Duplex (SR315070), Human cGAS shRNA Plasmid Kit (TL305813), and pCMV6-Entry Mammalian Expression Vector—were used for gene overexpression, knockdown, and control experiments to investigate the roles of CMPK2 and cGAS in microglial activation and neuroinflammation.
Snippet: CMPK2 and knockdown cGAS in BV2 cells, we obtained the CMPK2 (NM_207315) Human Tagged ORF clone (RC218794), CMPK2 Human siRNA Oligo Duplex (SR315070), and Human cGAS shRNA Plasmid Kit (TL305813) from OriGene Technologies (Rockville). Concurrently, the pCMV6-Entry Mammalian Expression Vector (Rockville) was acquired from OriGene Technologies(Rockville) as a control plasmid. One day before transfect
FigureFigureFigure
Showing 1-1 of 1 papers.
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