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KAT2A Human siRNA Oligo Duplex (Locus ID 2648)

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SKU
SR301765
KAT2A (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  $518.00
In Stock*

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Other products for "KAT2A or NM_021078"

Specifications
Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
KAT2A (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 2648)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_021078
UniProt ID Q92830
Synonyms GCN5; GCN5L2; hGCN5; PCAF-b
Summary KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 PubMed 19339690).supplied by OMIM, Sep 2009
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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Documents
Resources

file-alt Citations

Structural findings of cinnolines as anti-schizophrenic PDE10A inhibitors through comparative chemometric modeling
Mondal, Halder, Adhikari et al
Mol Divers (2014) 18 (3), 655-71 DOI: 10.1007/s11030-014-9523-9
Cited by 14
AI Summary: OriGene products contributed to this study by providing the PDE10A cDNA clone (Cat# RC211123) used for enzyme expression and the anti-PDE10A antibody (Cat# TA500239) employed in protein detection assays.
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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