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EDA Human siRNA Oligo Duplex (Locus ID 1896)

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SKU
SR301325
EDA (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  $518.00
In Stock*

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Other products for "EDA or NM_001005609"

Specifications
Specifications
Product Data
Purity HPLC purified
Quality Control Tested by ESI-MS
Sequences Available with shipment
Components
EDA (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 1896)
Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Stability One year from date of shipment when stored at -20°C.
Shipping Ambient
# of Transfections Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM).
Note Single siRNA duplex (10nmol) can be ordered.
Reference Data
RefSeq NM_001005609, NM_001005610, NM_001005611, NM_001005612, NM_001005613, NM_001005614, NM_001005615, NM_001399
UniProt ID Q92838
Synonyms ECTD1; ED1; ED1-A1; ED1-A2; EDA-A1; EDA-A2; EDA1; EDA2; HED; HED1; ODT1; STHAGX1; TNLG7C; XHED; XLHED
Summary The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. provided by RefSeq, Jul 2008
Performance Guaranteed OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency.

For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required).
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Documents
Resources

file-alt Citations

Ectodysplasin-A mRNA in exosomes released from activated hepatic stellate cells stimulates macrophage response
Marrero, Attal, Nimeri et al
Exp Cell Res (2022) 419 (2), 113297 DOI: 10.1016/j.yexcr.2022.113297
Cited by 9
AI Summary: OriGene’s siRNAs targeting ectodysplasin-A (EDA) (CAT# SR301325) and a scrambled control siRNA were used to knock down EDA expression in human hepatic stellate cells, enabling the study to demonstrate EDA mRNA’s role in exosome-mediated macrophage activation.
Snippet: Three different short inhibiting RNA (siRNA) sequences against ectodysplasin-A (EDA) and a scrambled siRNA (scr-siRNA;control) sequence were purchased from Origene Technologies (Rockville, MD. CAT# SR301325). Human aHSCs (TWNT4 and LX2) w
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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