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Cebpb Rat shRNA Plasmid (Locus ID 24253)

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SKU
TR710974
Cebpb - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 24253
Synonyms Il6dbp; NF-IL6; TCF5
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Cebpb - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 24253). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001301715, NM_001301720, NM_024125, NM_024125.1, NM_024125.2, NM_024125.3, NM_024125.4, NM_024125.5, NM_001301720.1, NM_001301715.1, BC129071
UniProt ID P21272
Summary This intronless gene encodes a member of the transcription factor family whose members contain a basic leucine-zipper domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. The encoded protein plays important roles in several cellular processes and in various diseases, including regulating cell proliferation, differentiation, apoptosis and neuroinflammation, and being involved in brain injury and inflammatory progression. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with different cellular localizations and distinct biological functions. provided by RefSeq, Sep 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

A delta-secretase-truncated APP fragment activates CEBPB, mediating Alzheimer's disease pathologies
Yao, Kang, Xia et al
Brain (2021)
Cited by 41
AI Summary: OriGene products contributed to this study by providing the human APBB1 (Myc-DDK-tagged, Cat. RC202003) plasmid and shRNA plasmids targeting Cebpb (Rat shRNA Plasmid, Cat. TR710974) and FE65/APBB1 (Human shRNA Plasmid Kit, Cat. TG306652), which were used to manipulate gene expression and investigate molecular mechanisms underlying Alzheimer's disease pathologies.
Snippet: …The human transcript variant 1 of APBB1 tagged with Myc-DDK at the C-terminus was purchased from Origene (Cat. RC202003). … TR710974);FE65 (APBB1) Human shRNA Plasmid Kit (Locus ID 322, Cat. TG306652). …
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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