Crem Rat shRNA Plasmid (Locus ID 25620)
Specifications
| Product Data | |
| Locus ID | 25620 |
|---|---|
| Synonyms | Icer |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Crem - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 25620). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001110860, NM_001271101, NM_001271102, NM_001271245, NM_001271246, NM_001271247, NM_001271248, NM_017334, NM_001110860.1, NM_001110860.2, NM_017334.1, NM_017334.2, NM_001271248.1, NM_001271246.1, NM_001271102.1, NM_001271245.1, NM_001271247.1, NM_001271101.1, BC078899, NM_013086 |
| UniProt ID | Q03061 |
| Summary | Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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