Hat1 Rat shRNA Plasmid (Locus ID 296501)
SKU
TR701308
Hat1 - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 296501 |
|---|---|
| Synonyms | MGC105743 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Hat1 - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 296501). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001009657, NM_001009657.1, BC087663 |
| UniProt ID | Q5M939 |
| Summary | Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding
Gruber, Geller, Lipchik et al
Mol Cell (2019) 75 (4), 711-724.e5 DOI: 10.1016/j.molcel.2019.05.034
Gruber, Geller, Lipchik et al
Mol Cell (2019) 75 (4), 711-724.e5 DOI: 10.1016/j.molcel.2019.05.034
Cited by 109
AI Summary: In this study, OriGene’s HAT1 shRNA (TL313105) and HAT1 overexpression plasmid (RC203307) were used to manipulate HAT1 expression levels, enabling the authors to investigate HAT1’s role in coordinating histone H4 production and acetylation.
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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