Pm20d1 Mouse shRNA Plasmid (Locus ID 212933)
Specifications
| Product Data | |
| Locus ID | 212933 |
|---|---|
| Synonyms | 4732466D17Rik; AI098026 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Pm20d1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 212933). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC120725, BC125395, NM_178079, NM_001357478, NM_178079.1, NM_178079.2, NM_178079.3, BC025830, BC049922 |
| UniProt ID | Q8C165 |
| Summary | Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Kim, Terrell, Li et al
Elife (2020) 9 DOI: 10.7554/eLife.55211
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