Dock5 Mouse shRNA Plasmid (Locus ID 68813)
Specifications
| Product Data | |
| Locus ID | 68813 |
|---|---|
| Synonyms | 1110060D06Rik; AI666732; AI956923; BC016533; E130320D18; lr2; rlc |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Dock5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 68813). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_177780, NM_177780.3, BC158135, BC016533, BC050992, BC158046, BC158138 |
| UniProt ID | B2RY04 |
| Summary | Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (PubMed:18396277). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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