Sorbs2 Mouse shRNA Plasmid (Locus ID 234214)
Specifications
| Product Data | |
| Locus ID | 234214 |
|---|---|
| Synonyms | 2010203O03Rik; 9430041O17Rik; A530071H08; Argbp2; mKIAA0777; nArgBP2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Sorbs2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 234214). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001205219, NM_001310707, NM_001310708, NM_172752, NM_172752.1, NM_172752.2, NM_172752.3, NM_172752.4, NM_001205219.1, BC031203, BC039163, BC151038, BC157944, BC166027, BC172140 |
| Summary | Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 (By similarity). May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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