Scn3a Mouse shRNA Plasmid (Locus ID 20269)
Specifications
| Product Data | |
| Locus ID | 20269 |
|---|---|
| Synonyms | Gm1000; Nav1.3 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Scn3a - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 20269). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_018732, NM_001355166, NM_001355167, NM_001355168, NM_001355169, NM_001355170, NM_001355171, NM_018732.1, NM_018732.2, NM_018732.3 |
| UniProt ID | A2ASI5 |
| Summary | Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:29142310). May contribute to the regulation of serotonin/5-hydroxytryptamine release by enterochromaffin cells (PubMed:29142310). In pancreatic endocrine cells, required for both glucagon and glucose-induced insulin secretion (PubMed:25172946).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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