Dlc1 Mouse shRNA Plasmid (Locus ID 50768)

SKU
TR519146
Dlc1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 50768
Synonyms A730069N07Rik; Arhgap7; dlc-1; HP; STARD12
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Dlc1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 50768). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001194940, NM_001194941, NM_015802, NM_001194940.1, NM_001194940.2, NM_015802.1, NM_015802.2, NM_015802.3, NM_001194941.1, BC150802, BC028562, BC048730, BC056230, BC096052
UniProt ID Q9R0Z9
Summary Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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