Dlc1 Mouse shRNA Plasmid (Locus ID 50768)
Specifications
| Product Data | |
| Locus ID | 50768 |
|---|---|
| Synonyms | A730069N07Rik; Arhgap7; dlc-1; HP; STARD12 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Dlc1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 50768). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001194940, NM_001194941, NM_015802, NM_001194940.1, NM_001194940.2, NM_015802.1, NM_015802.2, NM_015802.3, NM_001194941.1, BC150802, BC028562, BC048730, BC056230, BC096052 |
| UniProt ID | Q9R0Z9 |
| Summary | Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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