Tnp2 Mouse shRNA Plasmid (Locus ID 21959)
Specifications
| Product Data | |
| Locus ID | 21959 |
|---|---|
| Synonyms | Tp-2; TP2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Tnp2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 21959). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC092529, NM_013694, NM_013694.1, NM_013694.2, NM_013694.3, NM_013694.4 |
| UniProt ID | P11378 |
| Summary | Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals (PubMed:15163613, PubMed:15189834, PubMed:15083521, PubMed:28366643). In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction (PubMed:28366643). The histone H2AFB1-HIST1H2BA/TH2B dimer is required for loading of TNP2 onto chromatin (PubMed:28366643).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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