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Ccl11 Mouse shRNA Plasmid (Locus ID 20292)

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SKU
TR519095
Ccl11 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 20292
Synonyms eotaxin; Scya11
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Ccl11 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 20292). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC027521, NM_011330, NM_011330.1, NM_011330.2, NM_011330.3
UniProt ID P48298
Summary In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation
Xiao, Lee, Aguilera-Uribe et al
Cell Rep (2024) 43 (7), 114417 DOI: 10.1016/j.celrep.2024.114417
Cited by 18
AI Summary: In this study, OriGene’s NRBP1 antibody (TA500437) was used to investigate the role of NRBP1 in cell volume regulation and its functional interactions with TSC22D and WNK gene families.
Snippet: WNK1 Abcam ab137687;RRID:AB_11001564 NRBP1 Origene TA500437;RRID:AB_10712878 OSR1 Atlas HPA008237: RRID:AB_1854822
Autotaxin-lysolipid signaling suppresses a CCL11-eosinophil axis to promote pancreatic cancer progression
Bhattacharyya, Oon, Diaz et al
Nat Cancer (2024)
Cited by 41
AI Summary: In this study, OriGene products—including the ENPP2 rescue plasmid (MR200278L4) and CCL11 shRNA plasmids (TR519095, four unique 29-mer constructs)—were used to manipulate gene expression and investigate the role of autotaxin-lysolipid signaling in regulating eosinophil accumulation and pancreatic cancer progression.
Snippet: from Origene (MR200278L4). ENPP2 rescue plasmid was purchased from Origene ( CCL11 shRNA plasmids were purchased from Origene (TR519095, four unique 29-
Showing 1-2 of 2 papers.
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