Ano3 Mouse shRNA Plasmid (Locus ID 228432)
Specifications
| Product Data | |
| Locus ID | 228432 |
|---|---|
| Synonyms | AI838058; B230324K02Rik; Tmem16c |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ano3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 228432). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001081556, NM_001128103, NM_001355244, NM_001355245, NM_001355246, NM_001081556.1, NM_001128103.1, NM_001128103.2 |
| UniProt ID | A2AHL1 |
| Summary | Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide (PubMed:23532839). Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:23532839). Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity (PubMed:23872594).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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