Taf1 Mouse shRNA Plasmid (Locus ID 270627)
Specifications
| Product Data | |
| Locus ID | 270627 |
|---|---|
| Synonyms | 250kDa; AU015687; B430306D02Rik; Ccg-1; Ccg1; KAT4; N-TAF1; Taf2a; TAFII250 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Taf1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 270627). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001081008, NM_001290729, NM_001081008.1, NM_001290729.1, BC047418, BC050098, BC051073, BC094568, BC156425 |
| UniProt ID | Q80UV9 |
| Summary | Largest component and core scaffold of the TFIID basal transcription factor complex (PubMed:10438527). Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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