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Cyth1 Mouse shRNA Plasmid (Locus ID 19157)

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SKU
TR517243
Cyth1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 19157
Synonyms CLM1; CTH-1; CYTIP; Pscd1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Cyth1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 19157). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC057974, NM_001112699, NM_001112700, NM_011180, NM_001112699.1, NM_011180.1, NM_011180.2, NM_011180.3, NM_001112700.1, BC006658, NM_001112699.2, NM_001112700.2
UniProt ID Q9QX11
Summary Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6 (PubMed:18042453, PubMed:20080746). Promotes the activation of ARF factors through replacement of GDP with GTP (PubMed:18042453). Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity (PubMed:20080746, PubMed:29420262).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

A critical role of Arf6 in the response of commissural axons to Slit
Kinoshita-Kawada, Hasegawa, Hongu et al
Development (2019)
AI Summary: OriGene products contributed shRNAs against mouse Cyth1, Cyth2, Cyth3, Arf6, and a control shRNA (all in pRS shRNA vector), which were used for ex vivo electroporation to investigate the roles of these genes in commissural axon response to Slit.
Snippet: siCyth2 (Silencer Select, Ambion/Thermo Fisher Scientific) was as previously described (Li et al., 2012). For ex vivo electroporation into spinal cords, shRNAs against mouse Cyth1, Cyth2, Cyth3 and Arf6 (in pRS shRNA vector;Origene) were used. Control shRNA (shControl) was also obtained from Origene
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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