Arhgap10 Mouse shRNA Plasmid (Locus ID 78514)
Specifications
| Product Data | |
| Locus ID | 78514 |
|---|---|
| Synonyms | A930033B01Rik; PSGAP-m; PSGAP-s |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Arhgap10 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 78514). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_030113, NM_030113.1, NM_030113.2, BC156535, BC172679, NM_001363417, NM_001363418, NM_001363419, NM_001363420, NM_001363421 |
| UniProt ID | Q6Y5D8 |
| Summary | GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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