Steap4 Mouse shRNA Plasmid (Locus ID 117167)
Specifications
| Product Data | |
| Locus ID | 117167 |
|---|---|
| Synonyms | 1110021O17Rik; AI481214; Tiarp; Tnfaip9 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Steap4 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 117167). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC006651, NM_054098, NM_054098.1, NM_054098.2, NM_054098.3 |
| UniProt ID | Q923B6 |
| Summary | Integral membrane protein that functions as NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane (PubMed:16609065). Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (By similarity). Can also reduce Cu(2+) to Cu(1+) (PubMed:16609065). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (PubMed:17482547). Associated with obesity and insulin-resistance (By similarity). Involved in inflammatory arthritis, through the regulation of inflammatory cytokines (PubMed:19660107). Inhibits anchorage-independent cell proliferation (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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