Agbl5 Mouse shRNA Plasmid (Locus ID 231093)
Specifications
| Product Data | |
| Locus ID | 231093 |
|---|---|
| Synonyms | 4930455N08; 9430057O19Rik; CCP5 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Agbl5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 231093). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC057349, NM_001048190, NM_001048191, NM_001048192, NM_001048193, NM_001294262, NM_174849, NR_122116, NR_122117, NM_174849.1, NM_174849.2, NM_174849.3, NM_001048192.1, NM_001048192.2, NM_001294262.1 |
| UniProt ID | Q09M02 |
| Summary | Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins (PubMed:20519502, PubMed:21074048). In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6 (PubMed:25103237). Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS (PubMed:26829768).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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