Polr3d Mouse shRNA Plasmid (Locus ID 67065)
Specifications
| Product Data | |
| Locus ID | 67065 |
|---|---|
| Synonyms | 44kDa; 2810426M17Rik; AI326118; AW489084; BN51T; RPC4; TSBN51 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Polr3d - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 67065). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC016102, NM_001164082, NM_025945, NM_025945.1, NM_025945.3, NM_001164082.1 |
| UniProt ID | Q91WD1 |
| Summary | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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