Lef1 Mouse shRNA Plasmid (Locus ID 16842)
Specifications
| Product Data | |
| Locus ID | 16842 |
|---|---|
| Synonyms | 3000002B05; AI451430; Lef-1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Lef1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 16842). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC057543, NM_001276402, NM_001276403, NM_010703, NM_010703.1, NM_010703.2, NM_010703.3, NM_010703.4, NM_001276403.1, NM_001276402.1, BC038305 |
| UniProt ID | P27782 |
| Summary | Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1 (By similarity). Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIASG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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