Acvr2a Mouse shRNA Plasmid (Locus ID 11480)
Specifications
| Product Data | |
| Locus ID | 11480 |
|---|---|
| Synonyms | ActrIIa; Acvr2; TactrII |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Acvr2a - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 11480). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_007396, NM_007396.1, NM_007396.3, NM_007396.4, BC138823 |
| UniProt ID | P27038 |
| Summary | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6 (PubMed:23527555).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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