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Slc7a11 Mouse shRNA Plasmid (Locus ID 26570)

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SKU
TR515040
Slc7a11 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 26570
Synonyms 9930009M05Rik; AI451155; sut; xCT
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Slc7a11 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 26570). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_011990, NM_011990.1, NM_011990.2, BC141402, BC098374, BC141408
UniProt ID Q9WTR6
Summary Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Age-dependent oxidation of extracellular cysteine/cystine redox state (Eh(Cys/CySS)) in mouse lung fibroblasts is mediated by a decline in Slc7a11 expression
Zheng, Ritzenthaler, Burke et al
Free Radic. Biol. Med. (2018) 118, 13-22 DOI: 10.1016/j.freeradbiomed.2018.02.026
AI Summary: In this study, the OriGene mouse Slc7a11 plasmid was used to overexpress Slc7a11 in lung fibroblasts, enabling the authors to investigate the role of Slc7a11 in regulating age-dependent changes in extracellular redox state.
Snippet: Genetic manipulation of Slc7a11 expression in lung fibroblasts. Plasmid transfection was used to over-express Slc7a11 in old fibroblasts, while siRNA was used to knock down Slc7a11 in young fibroblasts. Plasmid encoding mouse Slc7a11 was from Origene Technologies
Showing 1-1 of 1 papers.
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