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Myf5 Mouse shRNA Plasmid (Locus ID 17877)

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SKU
TR515019
Myf5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 17877
Synonyms B130010J22Rik; bHLHc2; Myf-5
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Myf5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 17877). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC132144, NM_008656, NM_008656.1, NM_008656.2, NM_008656.3, NM_008656.4, NM_008656.5
UniProt ID P24699
Summary Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Recessive MYF5 Mutations Cause External Ophthalmoplegia, Rib, and Vertebral Anomalies
Di Gioia, Shaaban, Tüysüz et al
Am. J. Hum. Genet. (2018)
AI Summary: OriGene’s MYF5WT-FLAG plasmid (RC210156) was used to study the functional impact of MYF5 mutations by enabling expression and mutagenesis of the MYF5 protein in vitro.
Snippet: To assess whether the MYF5 p.Arg95Cys amino acid substitution impairs MYF5 transcriptional function, we obtained a MYF5 expressing plasmid with a C-terminal Myc-FLAG tag (MYF5WT-FLAG, RC210156, OriGene) and mutagenized the plasmid to substitute Arg95 with a cysteine (MYF5R95C-FLAG)
Showing 1-1 of 1 papers.
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