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Pla2g6 Mouse shRNA Plasmid (Locus ID 53357)

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SKU
TR515018
Pla2g6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 53357
Synonyms BB112799; iPLA(2)beta; iPLA2; iPLA2beta; PNPLA9
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Pla2g6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 53357). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC003487, BC052845, BC057209, NM_001199023, NM_001199024, NM_001199025, NM_016915, NM_016915.1, NM_016915.2, NM_016915.3, NM_016915.4, NM_001199024.1, NM_001199025.1, NM_001199023.1, BC049778
UniProt ID P97819
Summary Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Group VIA phospholipase A2 in both host and tumor cells is involved in ovarian cancer development
Li, Zhao, Wei et al
FASEB J (2010) 24 (10), 4103-16 DOI: 10.1096/fj.10-161356
Cited by 62
AI Summary: OriGene products contributed to this study by providing shRNA constructs (specifically, OriGene shRNA for iPLA(2)β) used to downregulate iPLA(2)β expression in ID8 ovarian cancer cells, enabling the researchers to investigate the enzyme’s role in tumor development.
Showing 1-1 of 1 papers.
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